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What happens if I stop taking tirzepatide?

A dated answer with its sources.

Released: · Last reviewed:

Researched By Dr. Parmis · Medical Researcher · Western University of Health Sciences

Medically Reviewed By Dr. Jonathan Snipes, MD · Kim Callender, NP (FNP-BC)

Last medically reviewed: · This page is informational and does not constitute medical advice.

Direct answer

Most people regain weight. In SURMOUNT-4, adults who switched to placebo after 36 weeks on tirzepatide regained 14% of their body weight over the next 52 weeks, while those who continued lost a further 5.5%. Talk to your prescriber before stopping or stepping down, and if cost is the reason, compare a lower-priced program or a maintenance dose before stopping outright.

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